A speed-accuracy trade-off (SAT) in behavioural decisions is known to occur in a wide range of vertebrate and invertebrate taxa. Accurate decisions often take longer for a given condition, while fast decisions can be inaccurate in some tasks. Speed-accuracy tactics are known to vary consistently among individuals, and show a degree of flexibility during colour discrimination tasks in bees. Such individual flexibility in speed-accuracy tactics is likely to be advantageous for animals exposed to fluctuating environments, such as changes in predation (...) threat. We therefore test whether individual speed-accuracy tactics are fixed or flexible under different levels of predation threat in a model invertebrate, the bumblebee Bombus terrestris. The flexibility of speed-accuracy tactics in a foraging context was tested in the laboratory using a ‘meadow’ of artificial flowers harbouring ‘robotic’ crab spider predators. We found that while the ranking of bees along the speed and accuracy continuums was consistent across two levels of predation threat, there was some flexibility in the tactics used by individual bees – most bees became less accurate at colour discrimination when exposed to predation threat when flower types were rewarding. The relationship between decision speed and accuracy was influenced by predator detectability and the risk associated with making incorrect choices during the colour discrimination task. Predator crypsis resulted in a breakdown in the relationship between speed and accuracy, especially when making an incorrect floral choice incurred a distasteful quinine punishment. No single speed-accuracy tactic was found to be optimal in terms of foraging efficiency under either predation threat situation. However, bees that made faster decisions achieved higher nectar collection rates in predator free situations, while accurate bees achieved higher foraging rates under predation threat. Our findings show that while individual bees remain relatively consistent in terms of whether they place greater emphasis on speed or accuracy under predation threat, they can respond flexibly to the additional time costs of detecting predators. (shrink)

Freedom and the Rule of Law takes a critical look at the historical beginnings of law in the United States, and how that history has influenced current trends regarding law and freedom. Anthony Peacock has compiled articles that examine the relationship between freedom and the rule of law in America. The rule of law is fundamental to all liberal constitutional regimes whose political orders recognize the equal natural rights of all.

In this article we discuss the ethical dilemmas facing performance evaluators and the "evaluatees" whose performances are measured in a business context. The concepts of role morality and common morality are used to develop a framework of behaviors that are normally seen as the moral responsibilities of these actors. This framework is used to analyze, based on four empirical situations, why the implementation of a performance measurement system has not been as effective as expected. It was concluded that, in these (...) four cases, unethical behavior (i.e. deviations from the ethical behaviors identified in the framework) provided, at least to some extent, an explanation for the lower than expected effectiveness of the performance measurement procedures. At the end of the paper we present an agenda for further research through which the framework could be further developed and systematically applied to a broader set of cases. (shrink)

Integrating large language models (LLMs) like GPT-4 into medical ethics is a novel concept, and understanding the effectiveness of these models in aiding ethicists with decision-making can have significant implications for the healthcare sector. Thus, the objective of this study was to evaluate the performance of GPT-4 in responding to complex medical ethical vignettes and to gauge its utility and limitations for aiding medical ethicists. Using a mixed-methods, cross-sectional survey approach, a panel of six ethicists assessed LLM-generated responses to eight (...) ethical vignettes.The main outcomes measured were relevance, reasoning, depth, technical and non-technical clarity, as well as acceptability of GPT-4’s responses. The readability of the responses was also assessed. Of the six metrics evaluating the effectiveness of GPT-4’s responses, the overall mean score was 4.1/5. GPT-4 was rated highest in providing technical (4.7/5) and non-technical clarity (4.4/5), whereas the lowest rated metrics were depth (3.8/5) and acceptability (3.8/5). There was poor-to-moderate inter-rater reliability characterised by an intraclass coefficient of 0.54 (95% CI: 0.30 to 0.71). Based on panellist feedback, GPT-4 was able to identify and articulate key ethical issues but struggled to appreciate the nuanced aspects of ethical dilemmas and misapplied certain moral principles.This study reveals limitations in the ability of GPT-4 to appreciate the depth and nuanced acceptability of real-world ethical dilemmas, particularly those that require a thorough understanding of relational complexities and context-specific values. Ongoing evaluation of LLM capabilities within medical ethics remains paramount, and further refinement is needed before it can be used effectively in clinical settings. (shrink)

This introduction to the special issue on ‘Ricoeur and the ethics of care’ is not a standard editorial. It provides not only an explanation of the central questions and a first impression of the articles, but also a critical discussion of them by an expert in the field of care ethics, Joan Tronto. After explaining the reasons to bring Ricoeur into dialogue with the ethics of care, and analyzing how the four articles of this special issue shape this dialogue, the (...) authors give the floor to Tronto. She focuses on the central issue at stake: what may be the value of a more abstract, conceptual approach for the ethics of care as a radically practice-oriented way of thinking? She argues that the four contributions too easily frame this value in terms of Ricoeur’s relational anthropology. Instead she points out that if the ethics of care is a kind of practice, it makes sense to think of such practices as necessarily building upon one another, expanding constantly the context and relationships upon which practices are built. In the final section the authors respond to Tronto’s framing of ‘practices all the way up’ by arguing that this approach need not be at odds with one inspired by Ricoeur’s conceptual thinking. Rather the two can be seen as different movements—upwards and downwards—that both contribute constructively to the shaping of the important intermediary zone between the practices and the abstract ideals. (shrink)

With the growing importance of China and other Asian economies in international business, both executives and academic researchers are eager to understand the unique aspects of Asian business practices. Extant literature suggests that market orientation has a positive effect on firm performance in China. However, the moral and social norms in China are very different from those in Western societies; a business orientation developed based on Confucius ethics, a core Chinese philosophy that affects China and many Asian economies, should provide (...) an alternative, or even better, explanation of Chinese companies’ business practices and successes than market orientation, which is developed in the West. On the basis of content analysis of ancient Chinese literature and case studies of recent events in Asian, this paper aims to propose Jun-zi orientation as a more cultural-specific organizational orientation alternative to market orientation for use in East Asian business context. Specifically, this paper provides extensive literature review on Jun-zi concept, a major concept in Confucianism and its five virtues. The effects of Jun-zi orientation and its five virtues on different aspects of business performance are also discussed. (shrink)

PurposeTo explore the mindfulness practice, its long-term effects, facilitators and barriers, in clinical clerkship students 2 years after participation in an 8-week mindfulness-based stress reduction training.MethodA qualitative study was performed by semi-structured in-depth interviews with 16 clinical clerkship students selected by purposive sampling. Students had participated in a MBSR training 2 years before and were asked about their current mindfulness practice, and the long-term effects of the MBSR training. Thematic analysis was conducted using the constant comparison method. Data saturation was (...) reached after 16 interviews.ResultsMost interviewees were still engaged in regular, predominantly informal, mindfulness practice, although some discontinued mindfulness practice and reported an “unchanged lifestyle.” Three main themes came forward; “focused attention and open awareness” during daily activities as core elements of long-term mindfulness practice; “changes in behavior and coping” that resulted from taking a pause, reflecting, recognizing automatic behavioral patterns and making space for a conscious response; “integration in personal and professional life” by enhanced enjoyment of daily activities, improved work-life-balance and making different career choices. Barriers and facilitators in starting and maintaining mindfulness practice were understanding and intention as “pre-conditions”; practical, personal, and professional factors of students in maintaining practice.ConclusionTwo years after participation in a MBSR training, many interviewees were still engaged in mindfulness practice contributing to both personal and professional changes. In light of the high clerkship demands, MBSR training could be a valuable addition to medical curricula, supporting medical students in developing necessary competencies to become well-balanced professionals. (shrink)

Ce texte est tiré de I. Baxmann et al., Arbeit und Rhythmus – Lebensformen im Wandel, Paderborn, Wilhelm Fink Verlag, 2009, p. 15-36. La traduction en a été assurée par Anthony Liébault et déjà mise en ligne par la revue Agôn. Nous remercions Inge Baxman de nous avoir autorisé à le reproduire ici. L'époque moderne et la critique de la conception séculaire du travail « Travailler, c'est danser ». Voilà ce que prétend Karl Bücher, économiste allemand originaire de Leipzig, (...) dans son ouvrage de 1896 intitulé - 1er XXe siècle – Nouvel article. (shrink)

Depression is a highly recurrent disorder with limited treatment alternatives for reducing risk of subsequent episodes. Acceptance and commitment therapy (ACT) and attention bias modification (ABM) separately have shown some promise in reducing depressive symptoms. This study investigates (a) if group-based ACT had a greater impact in reducing residual symptoms of depression over a 12-month follow-up than a control condition, and (b) if preceding ACT with ABM produced added benefits. This multisite study consisted of two phases. In phase 1, participants (...) with a history of depression, currently in remission (N= 244), were randomized to either receive 14 days of ABM or a control condition. In phase 2, a quasi- experimental design was adopted, and only phase-1 participants from the Sørlandet site (N= 124) next received an 8-week group-based ACT intervention. Self-reported and clinician-rated depression symptoms were assessed at baseline, immediately after phase 1 and at 1, 2, 6, and 12 months after the conclusion of phase 1. At 12-month follow-up, participants who received ACT exhibited fewer self-reported and clinician-rated depressive symptoms. There were no significant differences between ACT groups preceded by ABM or a control condition. There were no significant differences between ACT groups preceded by ABM or a control condition. Group-based ACT successfully decreased residual symptoms in depression over 12 months, suggesting some promise in preventing relapse. (shrink)

Berkeley’s ‘esse is percipi’ has been criticized for implying epistemological solipsism, the main argument being that different minds cannot harbor numerically one and the same idea. Similarly, C. J. Boström, the dominating Swedish philosopher in the nineteenth century, was early scorned because his principle of esse est percipi allegedly contradicts the simultaneous claim that two spirits can perceive the same thing under qualitatively different appearances. Whereas the criticism against Berkeley is here regarded as valid, it is argued that Boström successfully (...) defended himself by employing a dual concept of meaning, resembling Frege’s Sinn and Bedeutung some thirty years later, and by postulating an ontology that permits human minds to share in the divine ideas that constitute reality. (shrink)

Empathy is a fundamental concept in health care and nursing. In academic literature, it has been primarily defined as a personal ability, act or experience. The relational dimensions of empathy have received far less attention. In our view, individualistic conceptualizations are restricted and do not adequately reflect the practice of empathy in daily care. We argue that a relational conceptualization of empathy contributes to a more realistic, nuanced and deeper understanding of the functions and limitations of empathy in professional care (...) practices. In this article, we explore the relational aspects of empathy, drawing on sources that offer a relational approach, such as the field of care ethics, the phenomenology of Edith Stein and qualitative research into interpersonal and interactive empathy. We analyse the relational aspects of three prevalent components of empathy definitions: the underlying ability or act (i.e. the cognitive, affective and perception abilities that enable empathy); the resulting experience (i.e. empathic understanding and affective responsivity) and the expression of this experience (i.e. empathic expression). Ultimately, we propose four inter‐related understandings of empathy: (a) A co‐creative practice based on the abilities and activities of both the empathizer and the empathee; (b) A fundamentally other‐oriented experience; (c) A dynamic, interactive process in which empathizer and empathee influence each other's experiences; (d) A quality of relationships. (shrink)

Research suggests that sedentary behavior is negatively associated with cognitive outcomes. Interrupting prolonged sitting has been shown to improve cognitive functions, including executive functioning, which is important for academic performance. No research has been conducted on the effect of standing on EF in VET students, who make up a large proportion of the adolescent population and who are known to sit more than other students of this age. In this study, we investigated the acute effects of reducing SB by short (...) time standing on EF in vocational education and training students. In a randomized crossover study, 165 VET students were first taught for 15 min in seated position. After this, they performed while seated the Letter Memory Test for updating, and the Color Shape Test for shifting and inhibition. Students were randomly assigned to a sitting or standing condition. All students were taught again for 15 min and then took the same tests in the condition they were allocated to, respectively, standing or seated. After 1 week, the test procedure was repeated, in which students switched conditions. Mixed model analyses showed no significant effect of sitting or standing on updating, shifting, or inhibition. Also, no significant differences were found for the order of condition on updating, shifting, or inhibition. Our results suggest that 40 min of standing does not significantly influence EF among VET students. (shrink)

A foundation of quantum mechanics based on the concepts of focusing and symmetry is proposed. Focusing is connected to c-variables—inaccessible conceptually derived variables; several examples of such variables are given. The focus is then on a maximal accessible parameter, a function of the common c-variable. Symmetry is introduced via a group acting on the c-variable. From this, the Hilbert space is constructed and state vectors and operators are given a definite interpretation. The Born formula is proved from weak assumptions, and (...) from this the usual rules of quantum mechanics are derived. Several paradoxes and other issues of quantum theory are discussed. (shrink)

In this article, we report a study in which 109 research-active mathematicians were asked to judge the validity of a purported proof in undergraduate calculus. Significant results from our study were as follows: (a) there was substantial disagreement among mathematicians regarding whether the argument was a valid proof, (b) applied mathematicians were more likely than pure mathematicians to judge the argument valid, (c) participants who judged the argument invalid were more confident in their judgments than those who judged it valid, (...) and (d) participants who judged the argument valid usually did not change their judgment when presented with a reason raised by other mathematicians for why the proof should be judged invalid. These findings suggest that, contrary to some claims in the literature, there is not a single standard of validity among contemporary mathematicians. (shrink)

Do not be put off by the cumbersome title of this book. Underneath a huge mass of erudition lies a simple yet powerful thesis. The thinkers of the high Middle Ages did not imagine themselves as contributors to metaphysics, epistemology, logic, ethics, or any of the autonomous but interconnected “spheres of philosophical inquiry” that most post-Enlightenment historians of medieval philosophy take for granted. In very different ways, Aquinas, Scotus, and Ockham use the materials of philosophy to describe and illuminate the (...) movement of the human creature in via. The result may occasionally remind us of “doing philosophy,” but Inglis suggests that the similarities are mostly superficial. If we care about understanding medieval thought on its own terms, we will pay attention to the differences between the projects of modern philosophy and those of medieval theology—differences that are no less marked even when the latter self-consciously appropriates the insights of pagan philosophy. (shrink)

What do we owe those with whom we inquire? Presumably, quite a bit. Anything beyond what is necessary to secure knowledge? Yes. In this paper, I argue for a class of ‘zetetic rights.’ These are rights distinctive to participants in group inquiry. Zetetic rights help protect important central interests of inquirers. These include a right to aid, a right against interference, and a right to exert influence over the course of inquiry. Building on arguments by Fricker (2015), I defend these (...) rights, and explore cases of their violation: zetetic wrongings. I argue that zetetic wrongings constitute a distinctive, ubiquitous, and significant form of injustice in our epistemic and zetetic lives. To improve our inquiries and avoid epistemic injustice, we need to contend with zetetic wronging. Making this case helps show that a complete picture of epistemic life must account for the deep influence of our cooperative ties to one another. (shrink)

This paper presents the main topics, arguments, and positions in the philosophy of AI at present (excluding ethics). Apart from the basic concepts of intelligence and computation, the main topics of ar-tificial cognition are perception, action, meaning, rational choice, free will, consciousness, and normativity. Through a better understanding of these topics, the philosophy of AI contributes to our understand-ing of the nature, prospects, and value of AI. Furthermore, these topics can be understood more deeply through the discussion of AI; so (...) we suggest that “AI Philosophy” provides a new method for philosophy. (shrink)

... a vulnerable and fragmented work force.10 Based largely on oral history interviews, this ... THE TRUST The Trust was founded in 1970 by the Wisconsin Education Association ... of the National Staff Organization, an independent union represent- ing employees of teachers ' unions . ... \n.

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 39.3 (2001) 439-440 [Access article in PDF] John F. Wippel. The Metaphysical Thought of Thomas Aquinas: From Finite Being to Uncreated Being. Monographs of the Society for Medieval and Renaissance Philosophy, No. 1. Washington, D.C.: Catholic University Press, 2000. Pp. xxvii + 630. Cloth, $59.95. Paper, $39.95. In this weighty volume, John Wippel brings together much of the important research that he has (...) carried out on the metaphysics of Aquinas over the last three decades in order to produce as he calls it, a "Summa metaphysicae" based on the original texts of Aquinas (xxvii). Throughout much of the twentieth century metaphysics has been thought to be Aquinas's greatest philosophical achievement. The historical research of Etienne Gilson and Joseph Owens together with the philosophical reflections of Jacques Maritain did much to place this topic at the heart of Aquinas scholarship. Therefore, this volume both represents Wippel's central research interest and brings to a head an entire school of Aquinas studies of the twentieth century. It is the clearest and most detailed account of the subject in the English language, bearing the hallmarks of Wippel's scholarship: clarity in reference to the arguments and attention to textual chronology.Metaphysics here does not mean so much a focus on Aquinas's treatment of Aristotle's four causes or his act and potency as much as a clear presentation of Aquinas's reflections on existence (esse) and the implications that this has for his thought. After an introductory discussion of the nature and subject of metaphysics for Aquinas, Wippel devotes the first part of the book to Aquinas's view of existence in order to unpack what it means to talk about individual things as beings, being in general, and the catagories of Aristotle (73-74). Masterfully, he explains Aquinas's analogical approach to being and guides the reader through the interpretive thicket of Cornelio Fabro, G. P. Klubertanz, and Ralph McInerny. An interesting parallel is presented between Parmenides' problem of the one and the many and Aquinas's philosophically interesting view of the composite manner in which concrete individuals exist (161-170). Since no individual creature is the author of its own existence, but does in fact exist, each finite being must receive existence from a single being that exists necessarily. Wippel highlights this and other approaches that Aquinas takes to clarify relations between the many individual beings and the single divine being that lies beyond the study of metaphysics.Part two is devoted to many of the ways in which Aquinas talks about concrete individuals. Here Wippel explains Aquinas's distinctions between substance and accident as well as between matter and form and how they relate to existence. Part three concludes the work with a treatment of what Aristotle and Aquinas call divine science. This consists of more than a hundred pages on Aquinas's famous arguments for the existence of God (379-500) and a discussion of what human beings can understand about God (501-575). Not only does Aquinas conclude that God exists, but he indicates the limited manner in which human beings can understand the divine. The problem is that if we acquire language in relation to concrete individuals, how can we use words to discuss a being who is not bound by space or time? The solution is to speak of words like "good" and "wise" in an analogical sense. Words like these when applied to creatures are used in a sense that is both similar to but different from the way they are used to [End Page 439] speak of the divine. Reiterating the theme of the one and the many, the name "good" has a single and most excellent meaning when applied to God and a limited sense when applied to creatures.This is an excellent and accessible book for the educated reader and specialist alike which can be supplemented by works such as Wayne Hankey's God in Himself: Aquinas' Doctrine of God as Expounded in theSumma Theologiae (Oxford: Oxford... (shrink)

Sleep is consciousness naturally folded back to itself in the self-come-home-to-self, to find life nourished, renovated, and vitalized, all beyond objective management. Sleep can never be understood with direct conscious approach, but must be approached indirectly, implicatively, and alive coherently, as tried here. Sleep (A) is Spontaneity, (B) Self-Fullness, and so (C) sleep is life’s Gospel of Self-ing.

happens, how it happens, and why it happens. Our assumption ought to be that this is as true in education as it is in atomic physics. But this leaves many other questions to answer. The crucial ones: What kind of science is proper or appropriate to education? How does it differ from physics? What is wrong with the prevai1~ ing, virtually unopposed research tradition in education? What could or should be done to replace it with a more adequate tradi tion? (...) What concepts are necessary to describe and explain what we find there? It is in this realm that we find ourselves. Where to start? One place - our place, needless to say - is with one limited but central concept in education, teaching. A long philosophical tradition concerned with the nature of teaching goes back (along with everything else) to Plato, divulging most recent ly in the work of such philosophers as B. O. Smith, Scheffler, Hirst, Komisar, Green, McClellan, Soltis, Kerr, Fenstermacher, et al. An empirical tradition runs parallelto the philosophers -it has its most notable modern proponents in Gage, the Soars, Berliner, Rosen shine, but its roots can be traced to the Sophists. These two tradi tions have been at loggerheads over the centuries. (shrink)

Intended to give "a graphic picture of the development, relationship and relative importance of Chinese philosophical schools," this booklet contains 7 charts outlining the Ancient, the Middle, the Modern, the Sung, the Yuan and Ming, the Ch'ing, and the contemporary periods.--C. M.

The principle of energy conservation is widely taken to be a se- rious difficulty for interactionist dualism (whether property or sub- stance). Interactionists often have therefore tried to make it satisfy energy conservation. This paper examines several such attempts, especially including E. J. Lowe’s varying constants proposal, show- ing how they all miss their goal due to lack of engagement with the physico-mathematical roots of energy conservation physics: the first Noether theorem (that symmetries imply conservation laws), its converse (that conservation (...) laws imply symmetries), and the locality of continuum/field physics. Thus the “conditionality re- sponse”, which sees conservation as (bi)conditional upon symme- tries and simply accepts energy non-conservation as an aspect of interactionist dualism, is seen to be, perhaps surprisingly, the one most in accord with contemporary physics (apart from quantum mechanics) by not conflicting with mathematical theorems basic to physics. A decent objection to interactionism should be a posteri- ori, based on empirically studying the brain. (shrink)

Dictionary entry discussing the main moral and meta-ethical doctrines found in the works of James Griffin.

The essays in this volume, with the exception of Gary Ferngren's, derive from ancestral versions originally presented at a symposium, 'Conflicts with Newborns: Saving Lives, Scarce Resources, and Euthanasia: held May 10-12,1984, at the Mercer University School of Medicine, Macon, Georgia. We wish to express our gratitude to the Georgia Endowment for the Humanities for a generous grant for the symposium and to Mercer University and the Medical Center of Central Georgia for additional financial support. The vit:ws expressed in this (...) volume do not necessarily represent those of the Georgia Endowment for the Humani ties, Mercer University, or the Medical Center of Central Georgia. We have endeavored to bring together a group of individuals with contrast ing viewpoints to display some of the range of approaches to a major problem in public policy: medical decisions regarding the treatment of defective newborns. So many persons contributed to the symposium that acknowledg ment of each would be impossible. Although unnamed, we express our sincere appreciation to each. Three individuals, however, must be recognized: R. Kirby Godsey, President, Mercer University; William P. Bristol, Dean, Mercer University School of Medicine; and Kenneth C. Henderson, Medical Director and Director of Medical Education, Medical Center of Central Georgia. Without their support, the symposium could not have succeeded and this volume would not have been possible. We wish also to express our gratitude to S. G. M. (shrink)

Although the role of morphology in evolutionary theory remains a subject of debate, assessing the contributions of morphological investigation to evolutionary developmental biology (Evo-devo) is a more circumscribed issue of direct relevance to ongoing research. Historical studies of morphologically oriented researchers and the formation of the Modern Synthesis in the Anglo-American context identify a recurring theme: the synthetic theory of evolution did not capture multiple levels of biological organization. When this feature is incorporated into a philosophical framework for explaining the (...) origin of evolutionary innovations and novelties (a core domain of inquiry in Evo-devo) two specific roles for morphology can be described: (1) the conceptualization and operational identification of the targets of explanation; and (2) the elucidation of causal interactions at higher levels of organization during ontogeny and through evolutionary time. These roles are critical components of any adequate explanation of innovation and novelty though not exhaustive of the parts played by morphology in evolutionary investigation. They also invite reflection on what counts as an evolutionary cause in contemporary evolutionary biology. (shrink)

This chapter describes the theoretical implications of Extended Synthesis and addresses the methodological options available for determining aspects of theoretical structure. It uses a “bottom-up” approach focused on evolutionary theory in particular, as opposed to a “top-down” strategy that attempts to characterize the structure of all scientific theories. The chapter shows that there are multiple stable components contained within a broad representation of evolutionary theory. It suggests that the philosophical analysis offered in the chapter regarding the structure of evolutionary theory (...) assists attempts to recover coherence through the vehicle of an Extended Synthesis. (shrink)

The idea that sentences can be closer or further apart in meaning is highly intuitive. Not only that, it is also a pillar of logic, semantic theory and the philosophy of science, and follows from other commitments about similarity. The present paper proposes a novel way of comparing the ‘distance’ between two pairs of propositions. We define ‘\ is closer in meaning to \ than \ is to \’ and thereby give a precise account of comparative propositional similarity facts. Notably, (...) our definition eschews metric assumptions, which are unrealistic in most applications of interest. (shrink)

Psychiatric disorders present distinct clinical challenges which are partly attributable to their multifactorial aetiology and the absence of laboratory tests that can be used to confirm diagnosis or predict risk. Psychiatric disorders are highly heritable, but also polygenic, with genetic risk conferred by interactions between thousands of variants of small effect that can be summarized in a polygenic risk score. We discuss four areas in which the use of polygenic risk scores in psychiatric research and clinical contexts could have ethical (...) implications. First, there is concern that clinical use of polygenic risk scores may exacerbate existing health inequities. Second, research findings regarding polygenic risk could be misinterpreted in stigmatising or discriminatory ways. Third, there are concerns associated with testing minors as well as eugenics concerns elicited by prenatal polygenic risk testing. Fourth, potential challenges that could arise with the feedback and interpretation of high polygenic risk for a psychiatric disorder would require consideration. While there would be extensive overlap with the challenges of feeding back genetic findings in general, the potential clinical use of polygenic risk scoring warrants discussion in its own right, given the recency of this possibility. To this end, we discuss how lay interpretations of risk and genetic information could intersect. Consideration of these factors would be necessary for ensuring effective and constructive communication and interpretation of polygenic risk information which, in turn, could have implications for the uptake of any therapeutic recommendations. Recent advances in polygenic risk scoring have major implications for its clinical potential, however, care should be taken to ensure that communication of polygenic risk does not feed into problematic assumptions regarding mental disorders or support reductive interpretations. (shrink)

Thought: A Journal of Philosophy, Volume 10, Issue 3, Page 188-198, September 2021.

This paper focuses on abstraction as a mode of reasoning that facilitates a productive relationship between philosophy and science. Using examples from evolutionary developmental biology, I argue that there are two areas where abstraction can be relevant to science: reasoning explication and problem clarification. The value of abstraction is characterized in terms of methodology (modeling or data gathering) and epistemology (explanatory evaluation or data interpretation).

Developmental biology is the science of explaining how a variety of interacting processes generate an organism’s heterogeneous shapes, size, and structural features that arise on the trajectory from embryo to adult, or more generally throughout a life cycle. It represents an exemplary area of contemporary experimental biology that focuses on phenomena that have puzzled natural philosophers and scientists for more than two millennia.

Propositionalism is the claim that all logical relations can be captured by propositional logic. It is usually regarded as obviously false, because propositional logic seems too weak to capture the rich logical structure of language. I show that there is a clear sense in which propositional logic can match first-order logic, by producing formalizations that are valid iff their first-order counterparts are, and also respect grammatical form as the propositionalist construes it. I explain the real reason propositionalism fails, which is (...) more subtle and more interesting. (shrink)

Complete inferential rigour is achieved by breaking down arguments into steps that are as small as possible: inferential ‘atoms’. For example, a mathematical or philosophical argument may be made completely inferentially rigorous by decomposing its inferential steps into the type of step found in a natural deduction system. It is commonly thought that atomization, paradigmatically in mathematics but also more generally, is pro tanto epistemically valuable. The paper considers some plausible candidates for the epistemic value arising from atomization and finds (...) that none of them fits the bill. In particular, atomized arguments do not ground the correctness of their unatomized counterparts; they are typically not credence-preserving; and they need not reveal the source of inferential disagreement. The moral this suggests is that complete rigour is not even a defeasible epistemic ideal. (shrink)